Some reports maintain that a cold or other upper respiratory illness preceded the onset of SSNHL in as many as 40 percent of cases. Unfortunately, these reports lack corresponding data on the comparative frequency of upper respiratory illness in a matched control population. What about the evidence of blood examinations? In response to a virus, the immune system produces a temporary increase in the level of antibodies against the speciﬁc virus, and many case reports on patients with SSNHL show that they experience a brief, sharp rise in antibody levels against common viruses such as herpes, ﬂu, mumps, or rubella.
As of July 2012, a visit to the National Library of Medicine’s search engine, PubMed, revealed 497 research articles concerning AIED disease published since 1964 with eleven of these published in the last year. In spite of this moderate effort by the medical research community, AIED disease remains a chronic, incurable disorder that causes progressive disability to both hearing and balance. At the American Hearing Research Foundation (AHRF) , we have funded basic research on similar disorders in the past , and are interested in funding research on AIED in the future. We are particularly interested in projects that might lead to methods of stopping progression of hearing loss and the disabling attacks of dizziness. Get more information about contributing to the AHRF’s efforts to detect and treat acoustic neuroma.
Clinically, the success rate of Intratympanic steroid therapy in patients with SHL is variable in the literature and the available studies are limited to retrospective and non-controlled prospective ones. In those studies steroids were used in various concentrations, regimens and delivery methods and their effectiveness have not been established due to the lack of randomized controlled trials. There have been some studies in the literature that discussed the effectiveness of Intratympanic steroid therapy as a salvage mode of therapy in patients who failed to respond to oral steroids (Herr & Marzo 2005, Slattery et al 2005).