Omeprazole acts as an inhibitor of CYP2C19. Omeprazole, given in doses of 40 mg daily for one week to 20 healthy subjects in cross-over study, increased Cmax and AUC of cilostazol by 18% and 26% respectively. C max and AUC of one of its active metabolites, 3,4-dihydro-cilostazol, which has 4-7 times the activity of cilostazol, were increased by 29% and 69% respectively. Co-administration of cilostazol with omeprazole is expected to increase concentrations of cilostazol and its above mentioned active metabolite. Therefore a dose reduction of cilostazol from 100 mg twice daily to 50 mg twice daily should be considered.
Ive been smoking all kinds of spice for about 4 years now. im currently 5 days clean and ive never felt so great! ill admit i absolutely LOVED the stuff… Except the first couple times because i would freak out , but i just got blood results back i have no damage to kidney and everything in my body is healthy. i geuss its just different for some people.. Still, im not smoking it again since i feel amazing and i can eat regularly and sleep regularly. But yes it is bad. im not saying in anywway you should start smoking the stuff. it will ruin your life ive stolen from family and friends burned many bridges.. Please people dont start a viscous cycle..
I am a two-time survior of the devasting bacterial infection known as C-Diff. Since I am an otherwise completely healthy female (was 35 and 44 when I contracted), it was unexpected that the disease would nearly kill me – twice. I have taken liquid vancomycin for nearly nine months now, but it has not cured me. I had the good fortune of learning from my infectious disease doctor and obtaining an opinion from an expert at Johns Hopkins Hospital about my case, and both concurred that I should consider opting for a fecal transplant as vancomycin hasn’t cured me. Although the procedure is usually done at the hospital and is 90-95% effective (so I am told), my husband and I are doing the home-style version. A fecal transplant is done by taking the stole of a healthy, close family member, mixing it with saline solution in a blender, putting it through a seive, and “inplanting” the donor’s good bacteria via an enema bottle into your intestines via your rectum. Although it was quite disgusting the first day, it gets easier. I noticed a dramatic improvement within 12 hours. Anyone having gone through a severe case of C-Diff knows that the fecal transplant procedure is not nearly as tramatic and painful as living with this infection. Quite frankly, the fecal transplant may save my life.